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Prolozone Therapy is a regenerative injection technique that combines two powerful approaches in a single session: proliferative solutions plus medical ozone. First, a customized mixture of vitamins, minerals, nutrients and sometimes low-concentration dextrose is injected into the joint or painful area. Immediately afterward, a small amount of oxygen–ozone gas is injected into the same region.
In simple terms, Prolozone = Proliferative Therapy + Ozone Therapy in one treatment. This combination helps stimulate repair and regeneration of ligaments, tendons and cartilage, reduces inflammation, improves joint stability and increases oxygen availability in the tissues. The result is a more regenerative and longer-lasting effect than ozone alone, especially in joints and ligaments that have become lax or degenerated over time.
To actively repair and regenerate damaged or weakened ligaments, tendons and joint cartilage, not just calm inflammation. Prolozone is used when a true regenerative response is needed in painful, unstable or degenerated joints so patients can move with more stability and less chronic pain.
Early to moderate osteoarthritis (grade I–III), shoulder, knee or ankle instability, tendinopathies, ligament injuries, low back pain related to ligament laxity, patellofemoral pain syndrome and other forms of persistent or chronic musculoskeletal pain linked to joint degeneration or overuse.
Stimulates tissue repair and regeneration, reduces inflammation and pain, improves joint stability, enhances local oxygen delivery, and often provides a more durable result than ozone alone—helping delay or potentially avoid more aggressive procedures.







